Alessandro Furlan and Laurent Héliot co-authored an article in the journal eLife (IF 7.5).
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Alessandro Furlan and Laurent Héliot co-authored an article in the journal eLife (IF 7.5), which elucidates the role of the MET receptor in the processes of cell death and survival. In particular, the authors show that this receptor is capable of amplifying the death of hepatocytes under stress, and belongs to the family of so-called dependence receptors. In addition to shedding light on the architecture of cell signaling, this interdisciplinary work could open the door to new therapeutic strategies in the field of cancers > https://elifesciences.org/articles/50041
This publication was the subject of scientific news from the CNRS INSB > https://insb.cnrs.fr/fr/cnrsinfo/le-recepteur-met-une-des-clefs-de-lequilibre-des-forces-entre-vie-et-mort-cellulaire
and an extension article in The Conversation > https://theconversation.com/comment-nos-cellules-decident-si-elles-doivent-vivre-ou-mourir-138280
This publication was the subject of scientific news from the CNRS INSB > https://insb.cnrs.fr/fr/cnrsinfo/le-recepteur-met-une-des-clefs-de-lequilibre-des-forces-entre-vie-et-mort-cellulaire
and an extension article in The Conversation > https://theconversation.com/comment-nos-cellules-decident-si-elles-doivent-vivre-ou-mourir-138280
© David Tulasne @ Alessandro Furlan Figure: Section of a hepatic lobule of mouse liver, organized around a centrolobular vein, treated with an apoptosis inducer. A marking of the activated caspase 3 allows the detection in brown / red of the apoptotic cells at the periphery of the lobule.